Lamellar Bodies Count (LBC) as a Predictor of Fetal Lung Maturity in Preterm Premature Rupture of Membranes Compared to Neonatal Assessment

Background: Respiratory distress syndrome (RDS) is a major cause of neonatal morbidity and mortality, affecting approximately 1% all live births 10% preterm infants. Lamellar bodies represent storage form pulmonary surfactant within Type II pneumocytes, secretion which increases with advancing gestational age, thus enabling prediction the degree FLM. Preterm premature rupture membranes (PPROM) complicates 1/3 births. Birth 1 week most likely outcome for any patient PPROM in absence adjunctive treatments. has been reported to be common complication birth. Sepsis, intraventricular haemorrhage, necrotizing enterocolitis also are associated prematurity, but these less near term. Objective: To assess efficacy amniotic fluid lamellar body counting from vaginal pool predicting fetal lung maturity women membranes. Methods: This study was conducted at Ain Shams University Maternity Hospital emergency ward January 2019 September 2019. It included 106 singleton pregnancies, age 28 - 36 weeks designed (LBC) Results: The current revealed highly significant increase count cases giving birth neonates without RDS compared that RDS. Also, no statistically difference between LBC parity number previous miscarriages mother found. Gestational delivery significantly lower among respiratory distress. Steroid administration frequent However, had high diagnostic performance Conclusion: an effective, safe, easy, cost-effective method (FLM). does not need equipped laboratory or specially trained personnel, it just needs conventional blood analyzer. Measurement now replacing Lecithin/Sphyngomyelin L/S ratio. cut-off value ≤42.5 × 103/μL can used safely decide sensitivity 95.7% specificity 97.6%.